City of Frownsville

Cathy Cavadini

Blossom (voice)

Tara Strong

Bubbles (voice)

E. G. Daily

Buttercup (voice)

Tom Kenny

Mayor / Snake / Lil' Arturo / Narrator (voice)

Tom Kane

Professor Utonium / Him / Talking Dog (voice)

Roger L. Jackson

Mojo Jojo (voice)

Jennifer Martin

Ms. Sara Bellum (voice)

Jennifer Hale

Ms. Keane / Princess Morbucks / Sedusa (voice)

Jim Cummings

Fuzzy Lumpkins (voice)

Jeff Bennett

Ace / Grubber / Big Billy (voice)

Chuck McCann

The Amoeba Boys (voice)