Tom Hanks/Tom Petty and the Heartbreakers

Tim Meadows

Self - Various Characters

Norm Macdonald

Self - Various Characters

Molly Shannon

Self - Various Characters

Will Ferrell

Self - Various Characters

Jim Breuer

Self - Various Characters

Darrell Hammond

Self - Various Characters

Ana Gasteyer

Self - Various Characters

Chris Kattan

Self - Various Characters

Colin Quinn

Self - Various Characters

Mark McKinney

Self - Various Characters

Cheri Oteri

Self - Various Characters

Tracy Morgan

Self - Various Characters

Tom Petty

Self - Musical Guest

Tom Hanks

Self - Host

Steve Carell

Gary (voice) (uncredited)

Stephen Colbert

Ace (voice) (uncredited)

Patrick Ferrell

Dancer (uncredited)

Joe Ingenito

Prisoner (uncredited)

Adam McKay

Lab Technician (uncredited)

Peter Austin Noto

Various (uncredited)

Ryan Shiraki

Roxbury Dancer (uncredited)

Robert Smigel

Bighead (voice) (uncredited)